List of adverse effects of lurasidone

Lurasidone is an antipsychotic medication primarily used in the treatment of schizophrenia and bipolar disorder. Like all medications, lurasidone can have a range of adverse effects, which can vary in severity from mild to severe. This article aims to provide a comprehensive list of the known adverse effects associated with lurasidone, categorized by their frequency and severity. It is important for patients and healthcare providers to be aware of these potential adverse effects to manage them effectively.

Common Adverse Effects

Common adverse effects are those that occur more frequently and are generally mild to moderate in severity. Patients may experience these effects when they begin treatment with lurasidone but often find that they diminish over time.

• Akathisia (a feeling of restlessness)
• Nausea
• Vomiting
• Somnolence (drowsiness)
• Parkinsonism (motor symptoms similar to those seen in Parkinson's disease)
• Dystonia (involuntary muscle contractions)
• Insomnia

Uncommon Adverse Effects

Uncommon adverse effects are less frequent and can range from mild to severe. These effects may require medical attention and adjustments to the treatment regimen.

• Dyslipidemia (abnormal levels of lipids in the blood)
• Weight gain
• Orthostatic hypotension (a form of low blood pressure that happens when standing up from sitting or lying down)
• Hyperprolactinemia (elevated levels of prolactin in the blood)

Rare and Serious Adverse Effects

Rare and serious adverse effects are those that occur infrequently but can be severe and potentially life-threatening. Immediate medical attention is often required for these adverse effects.

• Neuroleptic Malignant Syndrome (NMS) (a life-threatening reaction that can cause a high fever, stiff muscles, confusion, abnormal thinking, and changes in heart rate and blood pressure)
• Tardive Dyskinesia (a condition involving involuntary movements, primarily of the face and tongue)
• Seizures
• Agranulocytosis (a severe drop in white blood cells, which can lead to an increased risk of infection)
• QT prolongation (a heart rhythm disorder that can potentially lead to sudden death)

Psychiatric Adverse Effects

In addition to the physical adverse effects, lurasidone can also have psychiatric adverse effects, which can affect a patient's mental health and behavior.

• Anxiety
• Depression
• Mania (in patients with bipolar disorder, lurasidone can induce manic episodes)

Conclusion

While lurasidone is an effective treatment for schizophrenia and bipolar disorder, it is important for patients and healthcare providers to be vigilant about the potential adverse effects associated with its use. Monitoring and managing these effects can help ensure the safety and well-being of patients undergoing treatment with lurasidone.

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