List of antiretroviral fixed-dose combinations
Antiretroviral fixed-dose combinations (FDCs) are formulations that combine two or more antiretroviral drugs into a single pill. These combinations are a cornerstone in the management of HIV/AIDS, simplifying treatment regimens by reducing the number of pills a patient needs to take, which can improve adherence and outcomes. This article provides a list of antiretroviral fixed-dose combinations, highlighting their components and uses in HIV treatment.
List of Antiretroviral Fixed-Dose Combinations[edit | edit source]
- Atripla - Combines Efavirenz, Emtricitabine, and Tenofovir disoproxil. It is used as part of a regimen for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg.
- Biktarvy - Combines Dolutegravir, Lamivudine, and Tenofovir alafenamide. It is indicated for the treatment of HIV-1 infection in adults and pediatric patients who have no antiretroviral treatment history or to replace the current antiretroviral regimen in those who are virologically suppressed.
- Genvoya - Combines Elvitegravir, Cobicistat (a pharmacokinetic enhancer), Emtricitabine, and Tenofovir alafenamide. It is approved for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 25 kg.
- Stribild - Similar to Genvoya but uses Tenofovir disoproxil instead of tenofovir alafenamide. It is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg.
- Odefsey - Combines Rilpivirine, Emtricitabine, and Tenofovir alafenamide. It is indicated for the treatment of HIV-1 infection in adults and pediatric patients who are virologically suppressed or new to antiretroviral therapy.
- Complera - Similar to Odefsey but uses Tenofovir disoproxil instead of tenofovir alafenamide. It is used for the treatment of HIV-1 infection in certain adults.
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