Fluspirilene

Fluspirilene is a diphenylbutylpiperidine antipsychotic drug, sold under the brand name Imap among others. It is classified as a typical antipsychotic and is used in the treatment of schizophrenia and other psychotic disorders.

Etymology

The term "Fluspirilene" is derived from its chemical structure, which consists of a fluoro group (Flu-), a spirane (spir-), and a piperidine (-ilene).

Pharmacology

Fluspirilene is a long-acting, injectable depot antipsychotic. It is a potent D2 receptor antagonist and also has high affinity for the D1 receptor. It has moderate affinity for the 5-HT2A receptor and low affinity for the 5-HT2C receptor.

Clinical Use

Fluspirilene is used primarily in the treatment of schizophrenia. It is also used in the treatment of other psychotic disorders, including bipolar disorder, paranoid disorder, and schizoaffective disorder.

Side Effects

Like other typical antipsychotics, fluspirilene can cause a range of side effects. These can include extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome, and anticholinergic effects.

See Also

• Antipsychotic
• Schizophrenia
• Psychotic disorders
• Diphenylbutylpiperidine

References

Fluspirilene Resources
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