Fluspirilene

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Fluspirilene is a diphenylbutylpiperidine antipsychotic drug, sold under the brand name Imap among others. It is classified as a typical antipsychotic and is used in the treatment of schizophrenia and other psychotic disorders.

Etymology[edit | edit source]

The term "Fluspirilene" is derived from its chemical structure, which consists of a fluoro group (Flu-), a spirane (spir-), and a piperidine (-ilene).

Pharmacology[edit | edit source]

Fluspirilene is a long-acting, injectable depot antipsychotic. It is a potent D2 receptor antagonist and also has high affinity for the D1 receptor. It has moderate affinity for the 5-HT2A receptor and low affinity for the 5-HT2C receptor.

Clinical Use[edit | edit source]

Fluspirilene is used primarily in the treatment of schizophrenia. It is also used in the treatment of other psychotic disorders, including bipolar disorder, paranoid disorder, and schizoaffective disorder.

Side Effects[edit | edit source]

Like other typical antipsychotics, fluspirilene can cause a range of side effects. These can include extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome, and anticholinergic effects.

See Also[edit | edit source]

References[edit | edit source]


Fluspirilene Resources
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