Lupus erythematosus panniculitis

Lupus erythematosus panniculitis (also known as Lupus panniculitis or Lupus profundus) is a rare form of lupus that primarily affects the fat tissue under the skin. It is characterized by inflammation and degeneration of the subcutaneous fat layer.

Symptoms

The most common symptom of lupus erythematosus panniculitis is the presence of firm, deep-seated nodules or plaques in the skin, particularly in the areas of the buttocks, thighs, upper arms, and face. These lesions may be painful and can lead to atrophy and scarring. Other symptoms may include fatigue, joint pain, and fever.

Causes

The exact cause of lupus erythematosus panniculitis is unknown. However, it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own tissues. It is also associated with other forms of lupus, such as systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE).

Diagnosis

Diagnosis of lupus erythematosus panniculitis is often challenging due to its rarity and nonspecific clinical presentation. It is typically confirmed through a combination of clinical findings, laboratory tests, and skin biopsy.

Treatment

Treatment for lupus erythematosus panniculitis primarily involves managing symptoms and preventing complications. This may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarial drugs, corticosteroids, and immunosuppressive agents.

See also

• Lupus erythematosus
• Autoimmune disease
• Systemic lupus erythematosus
• Discoid lupus erythematosus

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