Discoid lupus erythematosus

Discoid lupus erythematosus (DLE) is a chronic skin condition of sores with inflammation and scarring favoring the face, ears, and scalp and at times on other body areas. These lesions develop as a red, inflamed patch with a scaling and crusty appearance. The center areas may appear lighter in color with a rim darker than the normal skin.

Causes

DLE is caused by an abnormal immune response in which the body attacks its own healthy tissues. The exact cause of this abnormal response is unknown, but it is believed to be related to a combination of genetic, environmental, and hormonal factors.

Symptoms

The primary symptom of DLE is a rash that appears as red, inflamed, and scaly patches. These patches often leave scars when they heal. The rash is usually painless but may be accompanied by a burning sensation.

Diagnosis

Diagnosis of DLE is typically made through a combination of clinical examination, skin biopsy, and laboratory tests. The skin biopsy is particularly important in confirming the diagnosis, as it can reveal the characteristic changes in the skin that are indicative of DLE.

Treatment

Treatment for DLE primarily involves reducing exposure to sunlight and other sources of UV light, as these can worsen the condition. Topical corticosteroids and antimalarial drugs are commonly used to manage the symptoms of DLE.

Prognosis

While DLE can cause significant cosmetic concerns due to scarring, it does not typically affect a person's overall health or lifespan. However, a small percentage of people with DLE may go on to develop systemic lupus erythematosus, a more serious form of lupus that can affect multiple organs in the body.

See also

• Lupus erythematosus
• Systemic lupus erythematosus
• Cutaneous lupus erythematosus

References

Discoid lupus erythematosus Resources
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