Luteal support
Luteal Support is a medical term referring to the medical treatment given to women during the luteal phase of their menstrual cycle. This treatment is often used in assisted reproductive technology (ART) procedures such as in vitro fertilization (IVF) to increase the chances of pregnancy.
Overview[edit | edit source]
The luteal phase is the second half of a woman's menstrual cycle, which begins after ovulation and ends with the start of her period. During this phase, the body produces the hormone progesterone, which prepares the lining of the uterus for a potential pregnancy. If a woman's body does not produce enough progesterone, it can lead to a condition known as luteal phase defect (LPD), which can make it difficult for a woman to become pregnant or maintain a pregnancy.
Luteal support involves the administration of medications that contain progesterone to supplement the body's natural production. This can help to ensure that the lining of the uterus is adequately prepared for the implantation of an embryo.
Types of Luteal Support[edit | edit source]
There are several types of luteal support, including:
- Progesterone supplements: These can be administered orally, through injections, or through vaginal suppositories or gels. They are typically started after ovulation and continued until the pregnancy test is negative or until the 10th week of pregnancy if the test is positive.
- Human chorionic gonadotropin (hCG) injections: hCG is a hormone that stimulates the production of progesterone. It is often used in conjunction with progesterone supplements.
- Gonadotropin-releasing hormone (GnRH) agonists: These medications stimulate the production of progesterone and are often used in women undergoing IVF.
Effectiveness[edit | edit source]
Several studies have shown that luteal support can increase the chances of pregnancy in women undergoing ART procedures. However, the optimal type and duration of luteal support is still a topic of ongoing research.
Side Effects[edit | edit source]
Like all medications, those used for luteal support can have side effects. These can include bloating, breast tenderness, mood swings, and, in rare cases, ovarian hyperstimulation syndrome (OHSS).
See Also[edit | edit source]
- Menstrual cycle
- In vitro fertilization
- Progesterone
- Human chorionic gonadotropin
- Gonadotropin-releasing hormone
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Contributors: Prab R. Tumpati, MD