Adenosine monophosphate
(Redirected from Lycedan)
Adenosine Monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. AMP consists of a phosphate group, the sugar ribose, and the nucleobase adenine.
Structure and Properties[edit | edit source]
AMP is formed by the hydrolysis of both adenosine diphosphate (ADP) and adenosine triphosphate (ATP). The energy released during the hydrolysis of ATP and the phosphorylation of ADP to ATP is used in cellular metabolism.
AMP can be converted into inosine monophosphate (IMP) by the enzyme myoadenylate deaminase, freeing an ammonia molecule in the process.
Biological Role[edit | edit source]
In the cell, AMP activates some protein kinases, a type of enzyme that modifies other proteins by chemically adding phosphate groups to them. This process, known as phosphorylation, can activate or deactivate many enzymes and thus plays a crucial role in many cellular processes.
AMP also plays a role in cellular signaling as a component of cyclic AMP (cAMP), which is a crucial second messenger in many biological processes, including the response to hormones like adrenaline.
Clinical Significance[edit | edit source]
AMP is used clinically to treat specific heart rhythm disorders, such as atrial tachycardia. It can also be used to treat patients with adenosine deaminase deficiency, a rare genetic disorder.
See Also[edit | edit source]
References[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD