MDMAR
MDMAR (3,4-Methylenedioxy-N-methylamphetamine) is a psychoactive compound of the phenethylamine and amphetamine chemical classes. It is known for its potential use in psychotherapy and for recreational purposes.
Chemistry[edit | edit source]
MDMAR is a member of the methylenedioxyphenethylamine class, which is a group of compounds that are derivatives of phenethylamine. Its chemical structure consists of a phenethylamine core, with an additional methyl group attached to the nitrogen atom, and a methylenedioxy group attached to the benzene ring. This structure is similar to other psychoactive compounds such as MDMA and MDEA.
Pharmacology[edit | edit source]
The pharmacological action of MDMAR is primarily through its activity as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). This means it increases the levels of these neurotransmitters in the brain by inhibiting their reuptake into neurons. This leads to increased neuronal activity and stimulation.
MDMAR also has some activity as a releasing agent of these neurotransmitters, but this effect is less pronounced than its reuptake inhibition. The combination of these effects leads to the characteristic psychedelic and stimulant effects of MDMAR.
Effects[edit | edit source]
The effects of MDMAR can vary greatly depending on the dose, the individual's physiology, and the context in which it is used. Common effects include feelings of euphoria, increased energy, enhanced empathy and sociability, and altered perception. However, it can also cause negative effects such as anxiety, paranoia, and potentially dangerous increases in heart rate and blood pressure.
Risks and Safety[edit | edit source]
Like all psychoactive substances, MDMAR carries risks. These include potential for addiction, neurotoxicity, and serious adverse reactions. It is important for individuals to be aware of these risks and to use the substance responsibly.
Legal Status[edit | edit source]
The legal status of MDMAR varies by country. In some countries, it is classified as a controlled substance, while in others it is legal or unregulated.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
