MIR7-1

MIR7-1 is a gene that in humans is encoded by the MIR7-1 microRNA precursor. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression at the post-transcriptional level, playing a key role in various biological processes such as development, differentiation, apoptosis, and proliferation.

Function

The MIR7-1 gene is part of the microRNA family, which are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. MIR7-1 functions as a tumor suppressor in various types of cancer, including breast cancer, lung cancer, and glioma. It is also involved in the regulation of the insulin signaling pathway.

Clinical significance

Alterations in the expression of MIR7-1 have been associated with various types of cancer. For example, downregulation of MIR7-1 has been observed in glioblastoma multiforme, the most common and aggressive type of primary brain tumor. In addition, MIR7-1 has been implicated in the development of resistance to cancer treatments.

Research

Research into the role of MIR7-1 in cancer and other diseases is ongoing. Understanding the function of this gene and its role in disease could lead to the development of new therapeutic strategies.

MicroRNA molecule, which MIR7-1 gene encodes.

See also

• MicroRNA
• Gene expression
• Cancer