MT-45

MT-45 is a synthetic opioid that was first developed in the 1970s by the pharmaceutical company Dainippon Pharmaceutical. It is a piperazine derivative and has been used as a designer drug. MT-45 has been associated with several cases of serious toxicity and death.

History

MT-45 was first synthesized in the 1970s by Dainippon Pharmaceutical as part of a series of analgesic drugs. However, it was never marketed for medical use. In the 2010s, it began to appear on the recreational drug market as a designer drug.

Pharmacology

MT-45 is a synthetic opioid and acts as a mu-opioid receptor agonist. It has been found to have analgesic effects in animal studies. However, its potency is much lower than that of other commonly used opioids such as morphine or fentanyl.

Toxicity and Adverse Effects

Several cases of serious toxicity associated with MT-45 use have been reported. These include skin and eye damage, hearing loss, and respiratory depression. In some cases, use of MT-45 has resulted in death.

Legal Status

Due to its potential for abuse and serious health risks, MT-45 has been made illegal in many countries. It is classified as a Schedule I drug in the United States and a Class A drug in the United Kingdom.

See Also

• Opioid
• Designer drug
• Recreational drug use