McN5652
McN5652 is a serotonin transporter inhibitor that was developed for the treatment of depression. It is a radioligand that is used in positron emission tomography (PET) imaging to visualize the serotonin transporter in the brain.
History[edit | edit source]
McN5652 was developed in the 1990s as a potential treatment for depression. However, it was not successful in clinical trials due to its poor bioavailability and rapid metabolism. Despite this, it has found use as a radioligand in PET imaging.
Use in PET Imaging[edit | edit source]
In PET imaging, McN5652 is used to visualize the serotonin transporter in the brain. This is useful in studying conditions such as depression and anxiety disorders, which are thought to be linked to abnormalities in serotonin function.
Pharmacology[edit | edit source]
McN5652 is a potent and selective inhibitor of the serotonin transporter. It binds to the transporter and prevents the reuptake of serotonin, thereby increasing the amount of serotonin available in the brain.
Side Effects[edit | edit source]
As with all drugs, McN5652 has potential side effects. These can include nausea, vomiting, and dizziness. However, these side effects are generally mild and temporary.
See Also[edit | edit source]
| McN5652 Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
