Mestanolone
Mestanolone is an anabolic steroid that is derived from dihydrotestosterone (DHT). It is also known by its chemical name, 17α-methyl-DHT, and is sold under the brand name Androstalone.
History[edit | edit source]
Mestanolone was first synthesized in the 1950s by Syntex, a pharmaceutical company that was also responsible for the development of other anabolic steroids such as Oxymetholone and Methandrostenolone. Despite its early synthesis, Mestanolone did not gain widespread use until the 1970s.
Pharmacology[edit | edit source]
Mestanolone is a derivative of DHT, which means it does not convert to estrogen in the body. This makes it a popular choice for bodybuilders and athletes who want to avoid the water retention and gynecomastia that can occur with other steroids. However, like other DHT derivatives, Mestanolone can cause hair loss and prostate enlargement in men who are genetically predisposed to these conditions.
Medical Uses[edit | edit source]
Mestanolone has been used in the treatment of hypogonadism, a condition in which the body does not produce enough testosterone. It has also been used to treat delayed puberty in boys. However, due to its potential for side effects, it is not commonly used in medicine today.
Side Effects[edit | edit source]
The side effects of Mestanolone are similar to those of other anabolic steroids. These can include acne, hair loss, prostate enlargement, and increased aggression. In women, Mestanolone can cause virilization, which is the development of male characteristics such as deepening of the voice and growth of body hair.
Legal Status[edit | edit source]
In many countries, including the United States, Mestanolone is classified as a controlled substance. This means it is illegal to possess or distribute without a prescription.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD