Methoxymethylenedioxymethamphetamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

Methoxymethylenedioxymethamphetamine (MMDMA) is a synthetic molecule of the substituted amphetamine class. Molecules of this class are characterized by their structure which includes a phenethylamine core with an ethyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. MMDMA also contains methoxy, methylene, and dioxymethylene groups attached to the phenethylamine core, distinguishing it from other compounds in its class.

Chemistry[edit | edit source]

MMDMA belongs to the substituted methylenedioxyphenethylamine family, a subgroup of the substituted amphetamines. Its chemical structure is similar to that of methylenedioxymethamphetamine (MDMA), with the addition of a methoxy group. This modification potentially alters its pharmacological and toxicological profile compared to its more widely studied counterpart, MDMA.

Pharmacology[edit | edit source]

The pharmacological action of MMDMA is not well-documented due to its rarity and limited use in both clinical and recreational settings. However, based on its structural similarity to MDMA, it can be hypothesized that MMDMA acts as a releasing agent of serotonin, dopamine, and norepinephrine, potentially leading to euphoric, empathogenic, and stimulant effects. The addition of the methoxy group may influence its affinity for various neurotransmitter transporters and receptors, thereby modifying its effects.

Toxicology[edit | edit source]

The toxicological profile of MMDMA remains largely unknown. Given its structural similarity to MDMA, there may be risks of neurotoxicity, cardiotoxicity, and other adverse effects associated with amphetamines and their derivatives. Users of substances within this class should be aware of the potential for acute and long-term health risks.

Legal Status[edit | edit source]

The legal status of MMDMA varies by country, but it may be controlled under analog acts or specific legislation targeting psychoactive substances. In jurisdictions where analog acts are in place, MMDMA could be considered illegal if it is structurally similar to a controlled substance such as MDMA.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD