Methylenedioxyphencyclidine

Methylenedioxyphencyclidine (MDPC) is a psychoactive drug and research chemical of the arylcyclohexylamine class that has been sold online as a designer drug. It is an analog of phencyclidine (PCP) where the aromatic phenyl ring has been replaced by a benzodioxole ring.

Chemistry

MDPC is an arylcyclohexylamine in the same family as phencyclidine (PCP) and ketamine. The structure of MDPC includes a phenyl ring bonded to an amino group (NH2) through a cyclohexane ring. An additional benzodioxole ring is bonded to the same carbon location where PCP contains a phenyl ring.

Pharmacology

The pharmacological effects of MDPC are not well-studied. However, it is known to act as an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually this substance can cause an out-of-body experience.

Effects

The effects of MDPC can vary greatly depending on the dose taken. At lower doses, it can produce mild changes in perception, mood, and thought. At higher doses, it can lead to a state of complete dissociation from one's body and surroundings. This is similar to the effects of other dissociative drugs such as ketamine, DXM, and nitrous oxide.

Legal Status

The legal status of MDPC varies by country. In some countries, it is a controlled substance, while in others it is completely legal. It is important to check the legal status in your country before purchasing or using this substance.

See Also

• Phencyclidine
• Ketamine
• Dissociative
• NMDA receptor antagonist