Methylenedioxyphenmetrazine

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Methylenedioxyphenmetrazine

Methylenedioxyphenmetrazine (MDPM) is a psychoactive drug and research chemical of the phenmetrazine family, known for its stimulant and entactogen properties. It is structurally related to 3,4-methylenedioxyamphetamine (MDA) and phenmetrazine, a psychostimulant used as an appetite suppressant.

History

MDPM was first synthesized in the 1960s as part of a series of phenmetrazine analogs, but its psychoactive effects were not discovered until the 21st century when it began to appear on the research chemical market.

Pharmacology

MDPM acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), increasing levels of these neurotransmitters in the brain. This results in increased alertness, euphoria, and a sense of increased energy and focus. It also has entactogenic effects, promoting feelings of empathy and emotional closeness.

Effects

The effects of MDPM can vary greatly depending on the dose, individual physiology, and method of administration. Common effects include stimulation, euphoria, increased alertness, and enhanced sociability. At higher doses, it can cause anxiety, paranoia, and psychosis. Long-term use can lead to dependence and withdrawal symptoms.

Legal Status

The legal status of MDPM varies by country. In some countries, it is classified as a controlled substance, while in others it is legal to possess for personal use.

See Also

• Phenmetrazine
• Research chemical
• Psychoactive drug
• Stimulant
• Entactogen