Metizolam
Metizolam (marketed under the brand name Tranzilam) is a thienodiazepine drug which is a benzodiazepine analog. The effects of metizolam include anxiolytic, drowsiness, muscle relaxation, and amnesia which are typical of such drugs.
Pharmacology[edit | edit source]
Metizolam has been found to be roughly the same potency as diazepam, but with a slightly longer half-life. It is metabolized in the liver into the active metabolite alpha-hydroxymetizolam.
Medical Uses[edit | edit source]
Metizolam is used for the short-term treatment of insomnia, anxiety, and panic disorder. It is also used as a premedication for minor surgical procedures.
Side Effects[edit | edit source]
Common side effects of metizolam include drowsiness, dizziness, nausea, and dry mouth. More serious side effects may include respiratory depression, dependence, and withdrawal syndrome.
Interactions[edit | edit source]
Metizolam may interact with other medications, including other CNS depressants, alcohol, and grapefruit juice. These interactions can increase the risk of side effects and should be avoided.
Legal Status[edit | edit source]
In many countries, metizolam is a controlled substance due to its potential for abuse and dependence.
See Also[edit | edit source]
References[edit | edit source]
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