Mirizzi's syndrome

Mirizzi's syndrome is a rare complication of gallstones disease, which is characterized by mechanical obstruction of the common hepatic duct or the common bile duct. This obstruction is caused by a gallstone impacted in the cystic duct or the gallbladder neck.

Etiology

The exact cause of Mirizzi's syndrome is not known. However, it is believed to be due to the chronic inflammation and fibrosis that occurs in the gallbladder as a result of long-standing gallstones. This leads to the formation of a fistula between the gallbladder and the common hepatic duct, causing obstruction and jaundice.

Symptoms

The symptoms of Mirizzi's syndrome are similar to those of other gallstone diseases. They include:

• Jaundice
• Abdominal pain
• Fever
• Nausea
• Vomiting

Diagnosis

The diagnosis of Mirizzi's syndrome is often challenging due to its rarity and the nonspecific nature of its symptoms. It is usually made based on imaging studies such as ultrasound, computed tomography (CT) scan, and magnetic resonance cholangiopancreatography (MRCP).

Treatment

The treatment of Mirizzi's syndrome is surgical and involves the removal of the gallbladder (cholecystectomy), and in some cases, the repair of the fistula.

Prognosis

The prognosis of Mirizzi's syndrome is generally good with appropriate treatment. However, complications can occur, including bile duct injury and cholangitis.

See also

• Gallstones
• Cholecystectomy
• Cholangitis

References

Mirizzi's syndrome Resources
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