Monosulfiram

Monosulfiram is a synthetic organosulfur compound that is used as a scabicide in the treatment of scabies. It is applied topically in the form of a lotion or emulsion.

Chemistry

Monosulfiram is an organosulfur compound, which means it contains carbon, hydrogen, and sulfur atoms. It is a derivative of sulfiram, a compound that was first synthesized in the late 19th century. The chemical formula of monosulfiram is C10H20N2O2S.

Pharmacology

Monosulfiram works by killing the Sarcoptes scabiei mite, the organism that causes scabies. It is believed to do this by disrupting the mite's metabolism, although the exact mechanism of action is not fully understood. Monosulfiram is applied topically, usually in the form of a lotion or emulsion, and is absorbed through the skin.

Uses

The primary use of monosulfiram is in the treatment of scabies, a highly contagious skin condition caused by the Sarcoptes scabiei mite. It is also used to treat pediculosis, an infestation of lice.

Side Effects

Possible side effects of monosulfiram include skin irritation, rash, and allergic reactions. In rare cases, it can cause more serious side effects such as neurotoxicity.

See Also

• Scabies
• Pediculosis
• Organosulfur compounds
• Scabicide