Ms contin

MS Contin is a brand name for the drug Morphine Sulfate Extended-Release, a potent opioid medication used for the management of severe, chronic pain that requires around-the-clock treatment. It is manufactured by Purdue Pharma.

Pharmacology

Morphine, the active ingredient in MS Contin, is a powerful opioid analgesic that works by binding to mu-opioid receptors in the brain and spinal cord. This binding action inhibits the transmission of pain signals, providing relief from severe pain. The extended-release formulation of MS Contin allows for a steady release of morphine over a 12-hour period, providing long-lasting pain relief.

Indications

MS Contin is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. It is typically used in patients with chronic conditions such as cancer, neuropathic pain, and end-stage renal disease.

Side Effects

Like all opioids, MS Contin has potential side effects. These can include nausea, vomiting, constipation, drowsiness, and respiratory depression. Long-term use can lead to opioid dependence and opioid use disorder.

Contraindications

MS Contin is contraindicated in patients with known hypersensitivity to morphine, severe asthma or other respiratory problems, and paralytic ileus. It should be used with caution in patients with a history of substance abuse or mental illness.

See Also

• Opioid
• Morphine
• Purdue Pharma
• Opioid use disorder
• Chronic pain