Myeloperoxidase deficiency

Myeloperoxidase deficiency is a genetic disorder that affects the immune system. It is characterized by a decrease in the number of myeloperoxidase (MPO) enzymes, which play a crucial role in the immune response to infection.

Symptoms[edit | edit source]

The symptoms of myeloperoxidase deficiency can vary greatly from person to person. Some individuals with this condition may not show any symptoms at all, while others may experience frequent and severe infections.

Causes[edit | edit source]

Myeloperoxidase deficiency is caused by mutations in the MPO gene. This gene provides instructions for making the myeloperoxidase enzyme, which is found in certain types of white blood cells called neutrophils.

Diagnosis[edit | edit source]

Diagnosis of myeloperoxidase deficiency is typically made through a blood test that measures the level of myeloperoxidase in the blood. Genetic testing may also be used to identify mutations in the MPO gene.

Treatment[edit | edit source]

There is currently no cure for myeloperoxidase deficiency. Treatment is typically focused on managing symptoms and preventing infections. This may include the use of antibiotics and other medications.

Prognosis[edit | edit source]

The prognosis for individuals with myeloperoxidase deficiency can vary greatly depending on the severity of the condition and the individual's overall health. However, with proper management, many individuals with this condition can lead normal, healthy lives.

See also[edit | edit source]

Myeloperoxidase deficiency Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.