N-Desalkylflurazepam

N-Desalkylflurazepam is a benzodiazepine derivative and an active metabolite of several other benzodiazepine drugs including flurazepam, flutoprazepam, and midazolam. It is long-acting, and has anxiolytic properties.

Pharmacology

N-Desalkylflurazepam exhibits anxiolytic, sedative, muscle relaxant, and anticonvulsant properties. It acts on benzodiazepine receptors, which are found in high numbers in areas of the brain involved in emotion and memory, such as the hippocampus.

Metabolism

N-Desalkylflurazepam is metabolized in the liver by the cytochrome P450 enzyme system. It is excreted in the urine and feces.

Side effects

The side effects of N-Desalkylflurazepam are similar to those of other benzodiazepines, and may include drowsiness, ataxia, dysarthria, and fatigue. Long-term use of N-Desalkylflurazepam may result in tolerance, dependence, and withdrawal syndrome upon discontinuation.

See also

• Benzodiazepine
• Flurazepam
• Flutoprazepam
• Midazolam

N-Desalkylflurazepam Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski