N-Ethylheptedrone

N-Ethylheptedrone

N-Ethylheptedrone (also known as NEH and Ethyl-Hexedrone) is a stimulant compound of the cathinone class that produces traditional stimulant effects when administered. It is a part of a diverse group of substances called the substituted cathinones, all of which are derivatives of cathinone, the principal active component in the khat plant.

Chemistry

N-Ethylheptedrone is a cathinone, which is a group of drugs that are primarily classified as stimulants. Cathinones are beta-ketone analogues of amphetamine. In the case of N-Ethylheptedrone, the basic cathinone skeleton is modified by an ethyl group on the nitrogen atom and a heptan chain on the beta carbon.

Pharmacology

The pharmacology of N-Ethylheptedrone involves action as a norepinephrine-dopamine reuptake inhibitor (NDRI). It is believed to enhance levels of dopamine and norepinephrine in the brain by inhibiting their reuptake into neurons. This leads to increased concentration of these neurotransmitters in the synaptic cleft, resulting in increased stimulation of the post-synaptic neuron.

Effects

The effects of N-Ethylheptedrone can vary greatly depending on the dose, individual physiology, and method of administration. Common effects reported by users include stimulation, spontaneous physical sensations, euphoria, increased motivation, and increased sociability. Negative effects can include anxiety, paranoia, insomnia, and other typical stimulant side effects.

Legal Status

The legal status of N-Ethylheptedrone varies by country and is subject to change. As of now, it is a controlled substance in many countries due to its potential for abuse and addiction.

See Also

• Cathinone
• Stimulant
• Substituted cathinone
• Amphetamine

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