Nanoimpellers
Nanoimpellers are an experimental technology developed to eliminate some of the harmful effects of chemotherapy by facilitating treatment of only specific areas of the body. Nanoimpellers are nanoscale, light-activated containers filled with cancer-fighting drugs that only release their contents when hit by a specific type of laser.[1]
Nanoimpellers for cancer drug delivery were first demonstrated in 2008.[2][3] Initial work used ultraviolet light, however the low penetration in tissue and potential for toxicity mean this is not well suited for delivery in patients.[1] Later work has shifted to using near infrared light and two photon excitation (TPE) to trigger release.[4][5]
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Contributors: Prab R. Tumpati, MD
