Necrobiosis
Necrobiosis is a term used in pathology to refer to the death of cells which occurs as a part of the natural life cycle of an organism. This process is distinct from necrosis, which is a form of cell death that results from injury or disease. Necrobiosis is a normal physiological process that is essential for the maintenance of tissue homeostasis.
Types of Necrobiosis[edit | edit source]
There are several types of necrobiosis, including:
- Necrobiosis lipoidica: This is a rare skin disorder that typically affects the lower legs. It is characterized by shiny, red-brown patches that may become ulcerated and scarred over time. The exact cause of necrobiosis lipoidica is unknown, but it is often associated with diabetes mellitus.
- Necrobiosis lipoidica diabeticorum: This is a specific form of necrobiosis lipoidica that occurs in people with diabetes. It is more common in women than in men, and typically develops in young adults.
- Granuloma annulare: This is a skin condition characterized by raised, red or skin-colored bumps that form ring-shaped patterns. These bumps are caused by inflammation in the deeper layers of the skin, which is thought to be a form of necrobiosis.
Symptoms[edit | edit source]
The symptoms of necrobiosis depend on the specific type of the condition. In general, however, they may include:
- Red, brown, or yellow patches on the skin
- Skin that is shiny and may appear thinned or atrophied
- Lesions that may become ulcerated or scarred
- Itching or pain in the affected area
Diagnosis[edit | edit source]
The diagnosis of necrobiosis is typically made based on the appearance of the skin lesions. A biopsy may be performed to confirm the diagnosis and to rule out other conditions.
Treatment[edit | edit source]
Treatment for necrobiosis depends on the specific type of the condition and the severity of the symptoms. Options may include:
- Topical corticosteroids
- Phototherapy
- Laser therapy
- Surgical removal of lesions
See also[edit | edit source]
Necrobiosis Resources | ||
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