Neuropeptide Y receptor Y5

Neuropeptide Y receptor Y5 (also known as NPY5R) is a protein that in humans is encoded by the NPY5R gene. It is a G protein-coupled receptor that binds neuropeptide Y and peptide YY.

Function[edit | edit source]

The NPY5R is a receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It is involved in various biological processes including food intake, anxiety, circadian rhythm, and neuroendocrine secretion.

Gene[edit | edit source]

The NPY5R gene is located on the long arm of chromosome 4 (4q31.3-q32). It spans approximately 5.3 kilobases and consists of two exons. The gene is expressed in various tissues, including the brain, spleen, small intestine, and colon.

Clinical significance[edit | edit source]

Alterations in the NPY5R gene have been associated with obesity and eating disorders. In addition, the receptor has been implicated in the regulation of bone mass and energy homeostasis.

References[edit | edit source]

External links[edit | edit source]

NPY5R at HUGO Gene Nomenclature Committee
NPY5R at NCBI Gene

Template:GPCR-stub

This protein-related article is a stub. You can help WikiMD by expanding it.

‎

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.