Nigricans

Acanthosis Nigricans is a skin condition characterized by areas of dark, velvety discoloration in body folds and creases. The affected skin can become thickened. Most often, acanthosis nigricans affects your armpits, groin, and neck.

Causes

Acanthosis nigricans can result from obesity, or it can be inherited. It is also associated with various conditions related to insulin resistance, such as Type 2 diabetes and polycystic ovary syndrome (PCOS). In some cases, it is a warning sign of a cancerous tumor in an internal organ, such as the stomach or liver.

Symptoms

The symptoms of acanthosis nigricans include skin changes that typically occur in body folds. These changes include darkening of the skin, skin thickening, and a velvety texture. While it is not painful, the skin changes can cause cosmetic concerns and may signal underlying health issues.

Diagnosis

Diagnosis of acanthosis nigricans involves a physical examination by a healthcare provider. In some cases, additional tests may be required to determine the underlying cause, such as blood tests to check insulin levels or imaging studies to rule out internal tumors.

Treatment

Treatment for acanthosis nigricans focuses on addressing the underlying cause. If obesity is a factor, weight loss may improve the condition. For those with insulin resistance, medications to improve insulin sensitivity may be prescribed. In cases where acanthosis nigricans is linked to a tumor, treating the tumor can resolve the skin changes.

Prevention

Preventing acanthosis nigricans involves managing risk factors such as obesity and insulin resistance. Maintaining a healthy weight, eating a balanced diet, and regular exercise can help reduce the risk of developing this condition.

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