Nipah virus infection

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(Redirected from Nipah virus encephalitis)

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Nipah virus infection
File:Henipavirus structure.svg
Structure of Henipavirus
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Fever, headache, drowsiness, disorientation, mental confusion, coma
Complications Encephalitis, seizures, death
Onset 5 to 14 days after exposure
Duration 7 to 10 days
Types N/A
Causes Nipah virus
Risks Close contact with infected animals or humans
Diagnosis PCR, ELISA, virus isolation
Differential diagnosis Japanese encephalitis, herpes simplex encephalitis, rabies
Prevention Avoiding exposure to infected animals, biosecurity measures
Treatment Supportive care, intensive care
Medication N/A
Prognosis High mortality rate
Frequency Outbreaks in South Asia and Southeast Asia
Deaths Approximately 40% to 75% of cases


Nipah virus infection is a viral infection caused by the Nipah virus. Symptoms from infection vary from none to fever, cough, headache, shortness of breath, and confusion. This may worsen into a coma over a day or two. Complications can include inflammation of the brain and seizures following recovery.

File:Nipah virus from an infected VERO cell.jpg
Nipah virus from an infected VERO cell

Transmission[edit]

The virus is typically spread between people through direct contact with body fluids. It is also spread from animals such as pigs and bats to humans, with fruit bats being the most common source. Diagnosis is based on symptoms and confirmed by laboratory testing.

Prevention and Treatment[edit]

As of 2018, there is no vaccine or treatment that specifically targets Nipah virus infection. Efforts to prevent the infection involve avoiding exposure to bats in areas where the disease is common. When caring for those with the disease, standard infection control measures are important.

Epidemiology[edit]

Outbreaks have occurred in Malaysia, Singapore, India, and Bangladesh. The disease was first identified in 1999 during an outbreak among pig farmers in Malaysia and Singapore. The name of the virus comes from Sungai Nipah, a village in the Malaysian Peninsula where pig farmers became ill with encephalitis.

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