Nisoxetine

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Nisoxetine is a norepinephrine (noradrenaline) reuptake inhibitor that is used in scientific research. It was developed by Eli Lilly and was studied as an antidepressant, but was never marketed.

History[edit | edit source]

Nisoxetine was one of the first reuptake inhibitors to be developed. It was created by the pharmaceutical company Eli Lilly in the 1970s. Despite showing promise as an antidepressant, it was never marketed for this use.

Pharmacology[edit | edit source]

Nisoxetine acts primarily as a norepinephrine (noradrenaline) reuptake inhibitor. This means it increases the amount of norepinephrine in the brain by preventing it from being reabsorbed into nerve cells. This can have various effects on mood and behavior.

Research[edit | edit source]

Nisoxetine has been used in scientific research to study the role of norepinephrine in the brain. It has been used in studies investigating conditions such as depression, anxiety disorders, and attention deficit hyperactivity disorder (ADHD).

See also[edit | edit source]

References[edit | edit source]


Nisoxetine Resources
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Contributors: Prab R. Tumpati, MD