Non-cirrhotic portal fibrosis

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Non-cirrhotic portal fibrosis (NCPF) is a chronic liver disease[1] and type of non-cirrhotic portal hypertension (NCPH).

Presentation[edit | edit source]

It is characterized by 'obliterative portovenopathy', which leads to various problems such as portal hypertension, massive splenomegaly, and variceal bleeding. It is estimated that about 85% of people with NCPF have repeated episodes of variceal bleeding.[2]

Diagnosis[edit | edit source]

Hallmark of the disease is thrombosis/sclerosis of branches of portal vein. Vessels formed are often termed as mesangiosinusoids or periportal cavernoma.

Treatment[edit | edit source]

References[edit | edit source]

External links[edit | edit source]

Classification


Non-cirrhotic portal fibrosis Resources

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Contributors: Prab R. Tumpati, MD