Norelgestromin/ethinylestradiol
Norelgestromin/ethinylestradiol is a combination of two hormones, norelgestromin and ethinylestradiol, used in hormonal contraception. It is marketed under various brand names including Ortho Evra and Xulane.
Etymology[edit | edit source]
The name "norelgestromin" is derived from "norethindrone", a synthetic progestin, and "gestodene", a third-generation progestin. "Ethinylestradiol" is derived from "estradiol", a naturally occurring estrogen, and "ethinyl", indicating the addition of an ethinyl group.
Pharmacology[edit | edit source]
Norelgestromin/ethinylestradiol is a transdermal patch that releases the hormones norelgestromin and ethinylestradiol into the bloodstream. Norelgestromin is a progestin, or synthetic progesterone, which works by preventing ovulation and thickening cervical mucus to prevent sperm from reaching the egg. Ethinylestradiol is a synthetic estrogen that works in conjunction with the progestin to prevent ovulation.
Uses[edit | edit source]
Norelgestromin/ethinylestradiol is used as a method of birth control, to prevent pregnancy. It is also used to treat menstrual disorders, acne, and symptoms of premenstrual syndrome.
Side Effects[edit | edit source]
Common side effects of norelgestromin/ethinylestradiol include nausea, vomiting, headache, stomach cramping/bloating, breast tenderness, and weight change. Serious side effects include blood clots, stroke, and heart attacks.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
