Norelgestromin

Norelgestromin is a progestin medication which is used in hormonal contraception in combination with ethinylestradiol under the brand name Ortho Evra and Xulane. It is a prodrug of norgestimate, which, in the body, is transformed into levonorgestrel, a highly potent progestogen.

Medical Uses

Norelgestromin is used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception. Norelgestromin is used in combination with ethinylestradiol.

Pharmacology

As a progestin, norelgestromin has anti-estrogen effects. It works by inhibiting the release of an egg during the menstrual cycle.

Side Effects

Common side effects of norelgestromin include nausea, breast tenderness, headache, fatigue, mood changes, and abdominal pain. Serious side effects may include blood clots, heart attack, and stroke.

Interactions

Norelgestromin may interact with other drugs such as rifampin, ritonavir, St. John's wort, and seizure medications.

See Also

• List of progestogens
• List of progestogen esters
• Progestogen-only pill
• Combined oral contraceptive pill

Norelgestromin Resources
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