Nortetrazepam
Nortetrazepam is a benzodiazepine derivative. It is a minor active metabolite of diazepam, temazepam, and oxazepam. Nortetrazepam is known for its anxiolytic, anticonvulsant, sedative, and muscle relaxant properties.
Pharmacology[edit | edit source]
Nortetrazepam works by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA_A receptor, which results in its calming effects on the central nervous system (CNS). This mechanism is similar to other benzodiazepines.
Metabolism[edit | edit source]
Nortetrazepam is formed as a metabolite during the breakdown of diazepam, temazepam, and oxazepam in the body. The metabolic pathway involves the hepatic enzyme system, particularly the cytochrome P450 enzymes.
Medical Uses[edit | edit source]
Nortetrazepam is used in the treatment of various conditions, including:
- Anxiety disorders
- Insomnia
- Seizure disorders
- Muscle spasms
Side Effects[edit | edit source]
Common side effects of Nortetrazepam include:
Legal Status[edit | edit source]
The legal status of Nortetrazepam varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and dependence.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
