Norvinisterone

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Norvinisterone is a progestin medication which was developed by Syntex in the 1950s but was never marketed. It is a synthetic steroid and a derivative of testosterone.

History[edit | edit source]

Norvinisterone was synthesized in 1953 by the Mexican pharmaceutical company Syntex. It was one of the first progestins to be developed and was used in the initial studies of oral contraceptives, but was not included in the final product due to its androgenic effects.

Pharmacology[edit | edit source]

Norvinisterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has weak androgenic and glucocorticoid activity and no other important hormonal activity.

Society and culture[edit | edit source]

Although norvinisterone was never marketed, it has been used in scientific research.

See also[edit | edit source]

References[edit | edit source]

Norvinisterone Resources
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Contributors: Prab R. Tumpati, MD