O-Phenyl-3-iodotyramine

O-Phenyl-3-iodotyramine is a chemical compound that belongs to the class of organic compounds known as phenethylamines. It is a derivative of tyramine, a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. O-Phenyl-3-iodotyramine is characterized by the presence of an iodine atom on the phenyl ring.

Structure and Properties

O-Phenyl-3-iodotyramine consists of a phenyl group (a ring of six carbon atoms) attached to an amine group (NH2) through a two-carbon chain. The phenyl group is substituted at the 3-position with an iodine atom. The presence of the iodine atom significantly affects the compound's physical properties, including its density, melting point, and boiling point.

Synthesis

The synthesis of O-Phenyl-3-iodotyramine typically involves the iodination of tyramine. This process can be achieved through various methods, including electrophilic aromatic substitution.

Applications

While O-Phenyl-3-iodotyramine itself does not have significant biological activity, its derivatives have been studied for their potential applications in medicine and pharmacology. For example, radiolabeled derivatives of O-Phenyl-3-iodotyramine have been used in medical imaging to study the dopamine system in the brain.

Safety and Toxicity

As with all chemicals, safety precautions should be taken when handling O-Phenyl-3-iodotyramine. The compound's toxicity has not been extensively studied, but it is likely to be harmful if ingested or inhaled, and it may cause skin and eye irritation.

See Also

• Phenethylamine
• Tyramine
• Iodine
• Electrophilic aromatic substitution

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