OR10Z1

OR10Z1 is a gene that encodes a protein in the olfactory receptor family. This family is responsible for the detection of odor molecules, and the encoded protein is thought to play a role in the olfactory system. The OR10Z1 gene is located on chromosome 1 in humans.

Function

The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Structure

The OR10Z1 gene is located on the first chromosome in humans, specifically on the long arm at position 36.11. The gene spans approximately 1,000 base pairs and encodes a protein that is 312 amino acids in length. The protein encoded by OR10Z1 is a member of the olfactory receptor family, and like other members of this family, it has a 7-transmembrane domain structure.

Clinical Significance

While the specific role of OR10Z1 in human health and disease is not yet fully understood, olfactory receptors in general have been implicated in a variety of conditions, including anosmia, congenital anosmia, and Kallmann syndrome. Further research is needed to determine the specific role of OR10Z1 in these and other conditions.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 1

References

‎

---

Translate: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian