Oleoyl-estrone

From WikiMD's Food, Medicine & Wellness Encyclopedia

Oleoyl-estrone is a steroid and lipid molecule that has been studied for its potential effects on body weight and obesity. It is a derivative of the hormone estrone, with an oleoyl group attached.

Chemistry[edit | edit source]

Oleoyl-estrone is a lipophilic molecule, meaning it is soluble in fats and oils. It is composed of an estrone molecule, which is a type of estrogen, and an oleoyl group, which is a type of fatty acid. The oleoyl group is attached to the estrone molecule via an ester bond.

Biological Effects[edit | edit source]

Research has suggested that oleoyl-estrone may have effects on body weight and fat mass. In animal studies, administration of oleoyl-estrone has been shown to reduce food intake and body weight, potentially through effects on the hypothalamus, a region of the brain involved in regulating appetite. However, the exact mechanisms by which oleoyl-estrone exerts these effects are not fully understood.

Potential Therapeutic Uses[edit | edit source]

Due to its potential effects on body weight, oleoyl-estrone has been studied as a potential treatment for obesity. However, more research is needed to determine its safety and efficacy in humans.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD