Omeprazole/amoxicillin/rifabutin

Omeprazole/amoxicillin/rifabutin is a medication combination used in the treatment of Helicobacter pylori infection. This combination is marketed under the brand name Talicia.

Composition[edit | edit source]

The medication consists of three active ingredients:

Omeprazole, a proton pump inhibitor (PPI) that reduces stomach acid production.
Amoxicillin, an antibiotic that kills bacteria.
Rifabutin, another antibiotic that kills bacteria.

Uses[edit | edit source]

Omeprazole/amoxicillin/rifabutin is used to treat Helicobacter pylori infection, a bacterial infection that can cause stomach ulcers and is associated with stomach cancer.

Mechanism of action[edit | edit source]

Omeprazole reduces the production of stomach acid, which makes the environment less hospitable for Helicobacter pylori. Amoxicillin and rifabutin kill the bacteria directly.

Side effects[edit | edit source]

Common side effects of omeprazole/amoxicillin/rifabutin include diarrhea, headache, nausea, abdominal pain, rash, and taste disturbance.

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