P-Dimethylaminocinnamaldehyde
P-Dimethylaminocinnamaldehyde (often abbreviated as DMACA) is a chemical compound used primarily as a reagent in biochemical research. It is known for its ability to form a blue-colored complex upon reaction with flavanoids, which are a type of plant metabolite.
Chemical Structure and Properties[edit | edit source]
P-Dimethylaminocinnamaldehyde is an organic compound with the molecular formula C11H13NO. It is a derivative of cinnamaldehyde, the compound that gives cinnamon its flavor and aroma. The "P-" in its name refers to the para position of the dimethylamino group relative to the aldehyde group in the chemical structure.
DMACA is a yellow crystalline solid at room temperature. It is soluble in common organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but is less soluble in water.
Uses[edit | edit source]
The primary use of DMACA is as a reagent for the detection of flavanoids in a biochemical context. Flavanoids are a diverse group of plant metabolites with various biological activities, including antioxidant, anti-inflammatory, and anti-cancer properties. When DMACA reacts with flavanoids, it forms a blue-colored complex that can be detected visually or using spectroscopic methods.
DMACA is also used in the synthesis of certain organic compounds, particularly those with complex aromatic structures.
Safety[edit | edit source]
As with many chemical reagents, DMACA should be handled with care. It can cause skin and eye irritation, and may be harmful if swallowed or inhaled. Appropriate safety measures, including the use of personal protective equipment (PPE), should be taken when handling this compound.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD