PEAQX
Overview[edit | edit source]
PEAQX is a chemical compound known for its role as a selective antagonist of the AMPA receptor, a type of ionotropic glutamate receptor in the central nervous system. It is primarily used in neuroscience research to study the function of AMPA receptors and their involvement in synaptic transmission and plasticity.
Chemical Structure[edit | edit source]
PEAQX is a synthetic compound with a complex chemical structure that allows it to selectively bind to AMPA receptors. Its molecular formula is C18H18N4O4, and it is characterized by its ability to inhibit the activity of these receptors without affecting other types of glutamate receptors, such as NMDA receptors.
Mechanism of Action[edit | edit source]
PEAQX functions by binding to the AMPA receptor at the glutamate binding site, preventing the receptor from being activated by its natural ligand. This inhibition blocks the flow of sodium and calcium ions through the receptor channel, thereby modulating excitatory synaptic transmission in the brain. This property makes PEAQX a valuable tool in the study of neurophysiology and neuropharmacology.
Applications in Research[edit | edit source]
PEAQX is widely used in laboratory settings to investigate the role of AMPA receptors in various neurological processes. It is particularly useful in studies of long-term potentiation (LTP) and long-term depression (LTD), which are cellular mechanisms underlying learning and memory. By selectively blocking AMPA receptors, researchers can better understand their contribution to these processes and explore potential therapeutic targets for neurological disorders.
Safety and Handling[edit | edit source]
As with many research chemicals, PEAQX should be handled with care. It is important to follow appropriate safety protocols, including the use of personal protective equipment (PPE) and working in a well-ventilated area. Researchers should consult the material safety data sheet (MSDS) for detailed information on handling and potential hazards.
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