Para-Chlorophenylpiperazine

From WikiMD's Food, Medicine & Wellness Encyclopedia

Para-Chlorophenylpiperazine (pCPP) is a psychoactive drug and research chemical of the piperazine chemical class that has been sold online as a designer drug. It is a metabolite of the antidepressant drugs trazodone and nefazodone.

Chemistry[edit | edit source]

pCPP is a derivative of phenylpiperazine, a type of piperazine, and is chemically related to other drugs that have an aromatic phenyl ring attached to a piperazine core. A piperazine is a type of organic compound that contains a six-membered ring containing two nitrogen atoms at opposite positions in the ring. pCPP is classified as a substituted piperazine.

Pharmacology[edit | edit source]

pCPP acts as a serotonin receptor agonist, which means it increases the activity of the serotonin system in the brain. Serotonin is a neurotransmitter that is involved in the regulation of mood, appetite, and sleep. pCPP is also a partial agonist of the 5-HT2C receptor, which is involved in the regulation of mood and appetite.

Effects[edit | edit source]

The effects of pCPP on the human brain are not fully understood. However, it is known to produce psychoactive effects similar to those of other stimulant drugs. These effects may include feelings of euphoria, increased energy, and altered perceptions. It may also cause side effects such as anxiety, restlessness, and insomnia.

Legal Status[edit | edit source]

The legal status of pCPP varies by country. In some countries, it is a controlled substance, which means its manufacture, distribution, and use are regulated by law. In other countries, it is not controlled, but may be considered a research chemical, which means it is not approved for medical use and is often sold online for research purposes.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD