Para-Methoxymethamphetamine

Para-Methoxymethamphetamine (PMMA), also known as 4-methoxymethamphetamine, is a serotonin-releasing amphetamine that is related to methamphetamine and mescaline. It is often found in ecstasy tablets and is associated with severe side effects and deaths.

History

PMMA was first synthesized in the 1960s by the pharmaceutical company Upjohn but was never marketed. It reappeared on the illicit drug market in the 1990s.

Pharmacology

PMMA acts as a serotonin-releasing agent with weaker effects on dopamine and norepinephrine transporters. It also acts as a monoamine oxidase inhibitor (MAOI) with effects similar to mescaline.

Effects

The effects of PMMA are similar to those of MDMA (ecstasy), but it is considered more dangerous due to its higher potency, longer duration of action, and tendency to cause severe hyperthermia.

Health risks

PMMA has been associated with numerous deaths worldwide. It can cause severe hyperthermia, dehydration, seizures, heart failure, and serotonin syndrome. It is often sold as MDMA or ecstasy, increasing the risk of accidental overdose.

Legal status

PMMA is a controlled substance in many countries, including the United States, Canada, and many European countries.

See also

• MDMA
• Methamphetamine
• Mescaline
• Serotonin syndrome

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