Paris-Trousseau thrombocytopenia
Other Names: TCPT; Thrombocytopenia Paris-Trousseau type; Paris-Trousseau syndrome
Paris-Trousseau thrombocytopenia (TCPT) is a contiguous gene syndrome characterized by mild bleeding tendency, variable thrombocytopenia (THC), dysmorphic facies, abnormal giant alpha-granules in platelets and dysmegakaryopoiesis. Paris-Trousseau syndrome (PTS) is an inherited disorder characterized by mild hemorragic tendency associated with 11q chromosome deletion. It manifests as a granular defect within an individual's platelets. It is characterized by thrombocytes with defects in α-granule components which affects the cell's surface area and, consequently, its ability to spread when necessary.
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NIH genetic and rare disease info[edit source]
Paris-Trousseau thrombocytopenia is a rare disease.
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