Periventricular nucleus
Periventricular nucleus is a thin sheet of small neurons adjacent to the wall of the third ventricle in the brain. It is a part of the hypothalamus and plays a significant role in the endocrine system and autonomic nervous system.
Function[edit | edit source]
The periventricular nucleus is involved in the secretion of gonadotropin-releasing hormone (GnRH), thyrotropin-releasing hormone (TRH), and somatostatin. It also plays a role in the regulation of body temperature, food intake, and water balance.
Anatomy[edit | edit source]
The periventricular nucleus is located in the anterior part of the hypothalamus, adjacent to the third ventricle. It is a thin sheet of small neurons that extends from the optic chiasm to the mammillary bodies.
Clinical significance[edit | edit source]
Alterations in the function of the periventricular nucleus can lead to various disorders such as hypothyroidism, acromegaly, and precocious puberty. It is also implicated in the pathogenesis of neurodegenerative diseases like Parkinson's disease and Alzheimer's disease.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD