Alphenal

Alphenal (also known as Alphenal, Alfina, and Alfena) is a barbiturate derivative invented in the 1920s by a team at the pharmaceutical company Bayer. It has sedative and hypnotic effects, and was used for the treatment of insomnia.

History

Alphenal was first synthesized in the 1920s by a team at the pharmaceutical company Bayer. It was used for the treatment of insomnia and other sleep disorders. However, due to the development of safer and more effective medications, it is no longer commonly used.

Pharmacology

Alphenal, like other barbiturates, is believed to act as a positive allosteric modulator of the GABA_A receptor, the major inhibitory neurotransmitter in the brain. This enhances the effect of GABA, leading to sedative and hypnotic effects.

Side Effects

The side effects of Alphenal can include drowsiness, dizziness, nausea, and vomiting. In severe cases, it can cause respiratory depression, coma, and even death. It is also associated with a risk of dependence and withdrawal symptoms.

Interactions

Alphenal can interact with other medications, including other CNS depressants such as alcohol, benzodiazepines, and opioids. These interactions can increase the risk of side effects and can be potentially dangerous.

See Also

• Barbiturate
• GABA_A receptor
• Insomnia

References

Alphenal Resources
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