Phenescaline
Phenescaline is a psychedelic drug and phenethylamine derivative which is related to mescaline. It was first synthesized by Alexander Shulgin.
History[edit | edit source]
Phenescaline was first synthesized by Alexander Shulgin. In his book PiHKAL, Shulgin lists the dosage as 120-160 mg and the duration as 10–15 hours. He reports that phenescaline produces an array of psychedelic effects similar to those of mescaline, but with a less intense visual hallucination component.
Chemistry[edit | edit source]
Phenescaline, or 3,5-dimethoxy-4-phenethylphenethylamine, is a phenethylamine with the formula C16H21NO2. It is a member of the 2C family of psychedelic phenethylamines, all of which are derivatives of mescaline.
Pharmacology[edit | edit source]
Like other psychedelic phenethylamines, phenescaline likely acts as a 5-HT2A receptor agonist. The 5-HT2A receptor is responsible for many of the psychedelic effects produced by phenethylamines and other psychedelic drugs.
Effects[edit | edit source]
Phenescaline produces a range of psychedelic effects, including altered states of consciousness, visual hallucinations, and synesthesia. The effects are reported to be less intense than those of mescaline, but longer lasting.
Legal status[edit | edit source]
Phenescaline is not controlled at the federal level in the United States, but it could be considered an analog of a Schedule I drug under the Federal Analogue Act.
See also[edit | edit source]
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