Phenescaline
Phenescaline is a psychedelic drug and phenethylamine derivative which is related to mescaline. It was first synthesized by Alexander Shulgin.
History[edit | edit source]
Phenescaline was first synthesized by Alexander Shulgin. In his book PiHKAL, Shulgin lists the dosage as 120-160 mg and the duration as 10–15 hours. He reports that phenescaline produces an array of psychedelic effects similar to those of mescaline, but with a less intense visual hallucination component.
Chemistry[edit | edit source]
Phenescaline, or 3,5-dimethoxy-4-phenethylphenethylamine, is a phenethylamine with the formula C16H21NO2. It is a member of the 2C family of psychedelic phenethylamines, all of which are derivatives of mescaline.
Pharmacology[edit | edit source]
Like other psychedelic phenethylamines, phenescaline likely acts as a 5-HT2A receptor agonist. The 5-HT2A receptor is responsible for many of the psychedelic effects produced by phenethylamines and other psychedelic drugs.
Effects[edit | edit source]
Phenescaline produces a range of psychedelic effects, including altered states of consciousness, visual hallucinations, and synesthesia. The effects are reported to be less intense than those of mescaline, but longer lasting.
Legal status[edit | edit source]
Phenescaline is not controlled at the federal level in the United States, but it could be considered an analog of a Schedule I drug under the Federal Analogue Act.
See also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD