Phenmetrazine hydrochloride

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Phenmetrazine hydrochloride is a psychoactive drug and stimulant, which was previously used as an appetite suppressant, but has since been withdrawn from the market due to its potential for misuse and addiction.

History[edit | edit source]

Phenmetrazine was first synthesized in the 1950s and was marketed under the brand name Preludin. It was used as a treatment for obesity due to its appetite suppressant properties. However, due to its potential for misuse and addiction, it was withdrawn from the market in many countries in the 1970s and 1980s.

Pharmacology[edit | edit source]

Phenmetrazine hydrochloride acts as a norepinephrine-dopamine releasing agent (NDRA). It stimulates the release of these neurotransmitters in the brain, which results in increased alertness, focus, and reduced appetite. However, it also has the potential to cause a range of side effects, including insomnia, anxiety, and psychosis in high doses.

Legal status[edit | edit source]

In many countries, including the United States and the United Kingdom, phenmetrazine is classified as a controlled substance. This means that it is illegal to manufacture, distribute, or possess the drug without a valid prescription or license.

See also[edit | edit source]

References[edit | edit source]





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Contributors: Prab R. Tumpati, MD