Phloretin

From WikiMD's Food, Medicine & Wellness Encyclopedia

Phloretin is a dihydrochalcone, a type of natural phenol. It can be found in apple tree leaves and the Manchurian apricot.

Chemistry[edit | edit source]

Phloretin is a dihydrochalcone, a type of phenol. It is the aglycone part of phloridzin. It belongs to the group of flavonoids.

Natural occurrences[edit | edit source]

Phloretin can be found in apple tree leaves and the Manchurian apricot. It can also be found in strawberries and in ripe pears.

Research[edit | edit source]

Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2, though the inhibition is weaker than by its glycoside, phloridzin. It could reduce the vascular permeability for macromolecules and the adhesion of blood leukocytes in inflammation. It also possesses potent antioxidant activity.

See also[edit | edit source]

Phloretin Resources
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Contributors: Prab R. Tumpati, MD