Phthisis bulbi

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Phthisis bulbi
File:Phthisis bulbi, right eye.jpg
Phthisis bulbi of the right eye
Synonyms End-stage eye, Shrunken eye
Pronounce N/A
Specialty Ophthalmology
Symptoms Vision loss, eye pain, eye redness, shrunken eye
Complications Blindness, cosmetic disfigurement
Onset Variable
Duration Permanent
Types N/A
Causes Severe eye injury, inflammation, infection, retinal detachment, glaucoma
Risks Eye trauma, untreated eye disease
Diagnosis Clinical examination, imaging studies
Differential diagnosis Microphthalmia, enophthalmos
Prevention N/A
Treatment Prosthetic eye, enucleation, pain management
Medication N/A
Prognosis Poor for vision recovery
Frequency Rare
Deaths N/A


Phthisis bulbi is a degenerative condition of the eye characterized by shrinkage and disorganization of the intraocular contents. It is the end stage of various severe ocular diseases and injuries, leading to a non-functional eye.

Pathophysiology[edit]

Phthisis bulbi results from severe damage to the eye that leads to chronic inflammation, scarring, and atrophy of the ocular tissues. The condition can follow trauma, infection, or advanced glaucoma, among other causes. The eye becomes shrunken and disorganized, often with calcification and ossification of the intraocular structures.

Causes[edit]

Phthisis bulbi can be caused by:

Clinical Features[edit]

The clinical presentation of phthisis bulbi includes:

  • A shrunken, disorganized eye
  • Loss of vision
  • Pain, which may be present in some cases
  • Calcification or ossification within the eye

Diagnosis[edit]

Diagnosis of phthisis bulbi is primarily clinical, based on the history of ocular disease or trauma and the characteristic appearance of the eye. Imaging studies such as ultrasound or CT scan may be used to assess the extent of calcification or ossification.

Management[edit]

Management of phthisis bulbi focuses on alleviating symptoms and improving cosmetic appearance. Options include:

  • Enucleation or evisceration if the eye is painful
  • Fitting of a prosthetic eye for cosmetic purposes

Prognosis[edit]

Phthisis bulbi is an irreversible condition, and the affected eye is non-functional. The prognosis depends on the underlying cause and the presence of any complications.

Prevention[edit]

Preventive measures focus on early treatment of ocular diseases and injuries to prevent progression to phthisis bulbi. This includes prompt management of infections, control of intraocular pressure in glaucoma, and timely surgical intervention when necessary.

See also[edit]