Piperidic acid

Piperidic acid is an organic compound that belongs to the class of chemical compounds known as piperidines. It is a six-membered saturated heterocyclic compound with a nitrogen atom. Piperidic acid is a derivative of piperidine, where one hydrogen atom is replaced by a carboxylic acid group (-COOH).

Structure and Properties

Piperidic acid has a cyclic structure, with five carbon atoms and one nitrogen atom forming the ring. The carboxylic acid group is attached to one of the carbon atoms. The molecule is polar due to the presence of the carboxylic acid group, which also makes it capable of forming hydrogen bonds.

The molecular formula of piperidic acid is C5H9NO2, and its molecular weight is 115.13 g/mol. It is a solid at room temperature and is soluble in water due to its polar nature.

Synthesis

Piperidic acid can be synthesized from piperidine through a process known as oxidation. This involves the addition of an oxidizing agent, such as chromic acid, to the piperidine molecule. The reaction results in the formation of piperidic acid and a reduced form of the oxidizing agent.

Applications

Piperidic acid is used in the synthesis of various pharmaceuticals and other organic compounds. It is a key intermediate in the production of several antidepressants, antipsychotics, and antihistamines. It is also used in the synthesis of pesticides and other agrochemicals.

Safety and Precautions

Like many organic compounds, piperidic acid should be handled with care. It can cause irritation to the skin and eyes, and ingestion or inhalation can lead to harmful effects. Proper safety equipment, including gloves and eye protection, should be used when handling piperidic acid.

See Also

• Piperidine
• Carboxylic acid
• Organic compound
• Chemical synthesis