Pirprofen

Pirprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used in the treatment of pain and inflammation associated with conditions such as arthritis and gout. It is a member of the propionic acid class of NSAIDs, which also includes ibuprofen and naproxen.

Pharmacology

Pirprofen works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are chemicals in the body that cause inflammation and increase pain sensitivity. By blocking the production of these chemicals, pirprofen can reduce inflammation and alleviate pain.

Uses

Pirprofen is used to relieve pain and inflammation in a variety of conditions, including:

• Rheumatoid arthritis: A chronic inflammatory disorder that affects the joints.
• Osteoarthritis: A degenerative joint disease that results in the breakdown of joint cartilage and underlying bone.
• Gout: A type of arthritis characterized by sudden, severe attacks of pain, redness, and tenderness in joints.

Side Effects

Like all NSAIDs, pirprofen can cause side effects. These may include:

• Gastrointestinal problems: Such as stomach pain, heartburn, and nausea.
• Cardiovascular problems: Such as heart attack and stroke, particularly with long-term use.
• Renal problems: Such as kidney failure.

Patients should always discuss potential risks and benefits with their healthcare provider before starting treatment with pirprofen.

See Also

• Non-steroidal anti-inflammatory drug
• Cyclooxygenase
• Prostaglandin