Pirprofen
Non-steroidal anti-inflammatory drug
Pirprofen | |
---|---|
![]() | |
INN | |
Drug class | |
Routes of administration | |
Pregnancy category | |
Bioavailability | |
Metabolism | |
Elimination half-life | |
Excretion | |
Legal status | |
CAS Number | |
PubChem | |
DrugBank | |
ChemSpider | |
KEGG |
Pirprofen is a non-steroidal anti-inflammatory drug (NSAID) that was used for its analgesic and anti-inflammatory properties. It belongs to the class of propionic acid derivatives, which also includes other well-known NSAIDs such as ibuprofen and naproxen.
Pharmacology[edit | edit source]
Pirprofen works by inhibiting the cyclooxygenase (COX) enzymes, which are key in the synthesis of prostaglandins. Prostaglandins are lipid compounds that have several important roles in the body, including the mediation of inflammation and pain. By reducing the production of prostaglandins, pirprofen helps to alleviate symptoms of pain and inflammation.
Medical uses[edit | edit source]
Pirprofen was primarily used for the treatment of rheumatoid arthritis, osteoarthritis, and other musculoskeletal disorders. It was also used to relieve mild to moderate pain from various conditions, such as dysmenorrhea and dental pain.
Side effects[edit | edit source]
Like other NSAIDs, pirprofen can cause a range of side effects. Common side effects include gastrointestinal issues such as nausea, vomiting, and gastric ulceration. More serious side effects can include renal impairment, hepatic dysfunction, and hypersensitivity reactions.
Withdrawal[edit | edit source]
Pirprofen was withdrawn from the market in several countries due to concerns over its safety profile, particularly the risk of severe adverse drug reactions.
Chemical properties[edit | edit source]
Pirprofen is chemically classified as a propionic acid derivative. Its chemical structure is characterized by the presence of a propionic acid moiety, which is common among NSAIDs in this class.
Related pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD